BioXcell功能性抗體系列推薦-InVivoMAb anti-human CD3
產品信息：
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- 純度： >95%
- 內毒素：<2EU/mg
- 貨號：BE0001-2
- Clone: OKT-3
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應用類型：
in vitro T cell stimulation/activation
in vivo T cell depletion in humanized mice
ex vivo T cell inhibition for xenografts
Flow cytometry
參考文獻：
1、"Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig" PLoS One 10(4): e0122198.
2、"Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter" Eur J Immunol 45(4): 1103-1115.
3、"The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells" Mol Cell 59(5): 840-849.
4、"A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function" J Immunol 193(9): 4439-4447.
5、"CD8(+) MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis" Eur J Immunol 44(10): 3119-3128.
6、"Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles" J Immunol 193(2): 889-900.
7、"OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues" Blood 123(24): e134-144.
8、"VISTA is an immune checkpoint molecule for human T cells" Cancer Res 74(7): 1924-1932.
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