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2066 次 FAK 通過 Drp1 調(diào)控心肌細胞線粒體裂變和功能 2024-12-16
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1Keywords: Drp1; FAK; fibronectin; mitochondrial fission.線粒體對于心肌細胞的能量產(chǎn)生至關(guān)重要，其功能障礙與
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2516 次 機械應(yīng)力經(jīng)TGF-β1 激活 Smad2/3 并抑制 NF-κB 以防軟骨細胞焦亡 2024-12-16
Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthriti
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1502 次 動脈粥樣硬化中血流紊亂會損害MerTK介導(dǎo)的主動脈內(nèi)皮細胞的胞葬作用 2024-12-9
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosisKeywords: Disturbed flow; MerTK; RNA-seq; atherosclerosis; efferocytosis; prot
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1615 次 機械敏感的多囊蛋白1促進骨膜干/祖細胞在骨折愈合中的骨軟骨分化 2024-12-9
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healingKeywords: Fracture healing; Mechanical stress; Peri
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1332 次 TNFSF12/TWEAK調(diào)節(jié)結(jié)腸炎性成纖維細胞并促其與單核細胞相互作用 2024-12-2
The TNFSF12/TWEAK Modulates Colonic Inflammatory Fibroblast Differentiation and Promotes Fibroblast-Monocyte InteractionsKWS：TNFSF12/TWEAK；Colonic Inflammatory Fibroblast；Differ
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1120 次 miR-342-5p通過抑制 MYC增強內(nèi)皮細胞對剪切力的動脈化響應(yīng) 2024-12-2
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYCKeywords: MT: Non-coding RNAs; Notch; arterialization; end
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1438 次 激活的SIRT1 通過增強 H 型血管生成和骨形成的耦聯(lián)來促進骨修復(fù) 2024-11-25
SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesisKWS：SIRT1；bone repair；type H vessel formation；osteogenesis骨缺損可由感
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2145 次 血管內(nèi)皮細胞機械敏感基因在動脈粥樣硬化形成和治療中的研究進展 2024-11-25
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosisKeywords: Atherosclerosis; Blood flow; Endothelial cell; M
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1409 次 CD97 在壓縮下通過 Rap1a/ERK 通路抑制破骨細胞分化 2024-11-18
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compressionSubject terms: Orthodontics, Cell signalling正畸治療是通過正畸牙齒移動（OTM）矯正咬合不正。OTM 是一種
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2824 次 Piezo1 介導(dǎo)的機械轉(zhuǎn)導(dǎo)導(dǎo)致血流紊亂誘導(dǎo)的動脈粥樣硬化內(nèi)皮炎癥 2024-11-18
Piezo1‐Mediated Mechanotransduction Contributes to Disturbed Flow‐Induced Atherosclerotic Endothelial InflammationKeywords: Piezo1; atherosclerosis; endothelial cells; inflammati
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1341 次 綠茶化合物EGCG在子癇前期的體外靜態(tài)和剪切應(yīng)力模型中的抗氧化作用 2024-11-16
EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of PreeclampsiaKeywords: EGCG; NO; antioxidant; endotheli
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1307 次 電壓門控性鈣通道α2δ亞基-1調(diào)控結(jié)腸癌進展并影響其微環(huán)境 2024-10-28
CACNA2D1 regulates the progression and influences the microenvironment of colon cancerKeywords: CACNA2D1; Colon cancer; Fibroblast; Voltage-gated calcium channel; p53.近年來，由于化
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1080 次 人牙周膜間充質(zhì)基質(zhì)細胞通過旁分泌和細胞接觸介導(dǎo)對CD4+T的免疫調(diào)節(jié) 2024-10-28
Paracrine- and cell-contact-mediated immunomodulatory effects of human periodontal ligament-derived mesenchymal stromal cells on CD4+ T lymphocytesKeywords: CD4+ T lymphocytes; Co-
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1257 次 衰老誘導(dǎo)內(nèi)皮受損金屬蛋白酶17脫落連接粘附分子-A導(dǎo)致動脈重塑 2024-10-28
Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17Keywords: Aging; Endothelium dysfunction; F11R; Junc
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1612 次 BACH1 基因的缺失通過減少內(nèi)皮炎癥減輕動脈粥樣硬化 2024-10-28
Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial InflammationKeywords: BACH1; YAP; atherosclerosis; endothelial inflammation; hemodynamics.動脈粥樣硬化是冠狀動脈
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1240 次 流體剪切應(yīng)力通過NKG2D增強自然殺傷細胞對循環(huán)腫瘤細胞的細胞毒性 2024-10-25
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensingTopics：Mechanical stress, Cytotoxicity, Degr
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1376 次 與體外循環(huán)相關(guān)剪切應(yīng)力誘導(dǎo)單核細胞炎性細胞因子和壞死性凋亡的表達 2024-10-25
Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytesKeywords: Calcium signaling; Cardiology; Cytokines; Inf
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1528 次 線粒體蛋白去琥珀�；ㄟ^調(diào)節(jié)線粒體穩(wěn)態(tài)介導(dǎo)壓縮誘導(dǎo)的椎間盤退變 2024-10-25
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasisSubject terms: Dise
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1662 次 電壓門控性鈣通道α2/δ亞基-1調(diào)控結(jié)腸癌的進展并影響結(jié)腸癌的微環(huán)境 2024-10-21
近年來，由于化療的進步和分子靶向藥物的出現(xiàn)，結(jié)腸癌（CC）的治療結(jié)果有所改善。離子轉(zhuǎn)運體（Ion transporters）在細胞功能中起著至關(guān)重要的作用，近年來作為癌癥的潛在治療靶點而受到關(guān)注。闡
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1433 次 衰老致內(nèi)皮剪切應(yīng)力感損去整合素金屬蛋白酶介導(dǎo)粘附分子脫落動脈重塑 2024-10-21
隨著年齡的增長，心血管系統(tǒng)發(fā)生了重要變化，包括血管硬度升高和異常重塑。研究表明，與衰老相關(guān)的小阻力動脈重塑可以獨立于全身血壓的變化而發(fā)生。研究已表明，小阻力動脈會因血流的持久變化或
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